What is Difference Between Enzymes And Hormones?

Difference Between Enzymes And Hormones is that :

Enzymes are biological catalysts produced by a living organism that acts to produce a specific biochemical reaction.Difference Between Enzymes And Hormones

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Hormones are regulatory substances, usually, a peptide (e.g., insulin) or a steroid (e.g., estrogen), produced in an organism and transported in tissue fluids such as blood or sap to stimulate the activation of cells or tissues specific. Therefore, they are more an effector molecule (i.e. inducer/activator or repressor), this can be elaborated considering the case of insulin, which is a hormone, plays an important role in glucose metabolism, that is, glycolysis, which is carried out by enzymes, insulin activates the GLUT-IV transporter that facilitates the entry of glucose into the cell and, in turn, begins glycolysis.

Some other differences between enzymes and hormones are as follows:

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  • Do birth control pills balance your hormones?
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  • What are the side effects of injecting 100 mg of testosterone a week?

Enzymes: –


All enzymes are proteins, except some (composed of RNA, e.g., Hammerhead Ribozyme)


They are macromolecules of greater molecular weight


They are not diffusible through the cell membrane


Either they act intracellularly or are transported by some ducts to another site


Always act as biological catalysts and increase the rate of metabolic physiological processes.


They catalyze reversible or irreversible reactions.


The reaction rate increases with increasing concentration to a limit.


Act quickly

Hormones: –


They can be proteins, amines or steroids


They have an only low molecular weight


They are diffusible through the cell membrane


Generally transported by the blood to a target organ


They can be excitatory or inhibitory in their action


Hormone controlled reactions are not reversible.


Hormone deficiency or overproduction causes metabolic disorders or diseases


Some hormones are fast-acting, while others are slow-acting with a period of delay.

Differences between enzymes and hormones

Enzymes are the biological catalyst that accelerates the rate of biochemical reactions without experiencing any change.

Hormones are molecules, usually a peptide (for example, insulin) or steroid (for example, estrogen) that is produced in a part of an organism and triggers specific cellular reactions in target tissues and organs at a certain distance.




Most enzymes carry out reactions at the place of origin, that is, in the cells where they are produced.

The hormones perform an activity at a certain distance from the site of origin.


Enzymes are a biological catalyst. They catalyze biological reactions.

Hormones are not catalysts. They simply initiate biochemical reactions.


All enzymes are generally proteins. There are some exceptions such as ribozymes (RNA with catalytic activity).

The hormones can be polypeptides, terpenoids, steroids, phenolic compounds or amines.


Enzymes do not translocate from one part to another part of the cell.

Most hormones show polar translocation.


Since enzymes are catalysts, they remain unchanged at the end of the reaction and can be reused.

Since hormones are not catalysts, they participate in biological reactions and their chemical composition changes and cannot be reused as such.


They are macromolecules with greater molecular weight.

They have only low molecular weight.


They are not diffusible through the cell membrane.

They are diffusible through the cell membrane.


Either they act intracellularly or are transported by some ducts to another site.

Generally carried by the blood to an objective organ.


Increases the rate of metabolic physiological processes.

They can be excitatory or inhibitory in their actions.


They catalyze reversible reactions.

Hormone controlled reactions are not reversible.


The reaction rate increases with increasing concentration to a limit.

Hormone deficiency or overproduction causes metabolic disorders or diseases.


They act fast.

Some hormones are fast-acting, while others are slow-acting with a period of delay.


They are not used in metabolic functions.

They are used in metabolic functions.


They cannot regulate morphogenesis.

They usually regulate morphogenesis, especially secondary sexual character.



– Oxidoreductases

– Transferases

– Hydrolases


– Insulin,

– Glucagon,

– T3, T4,

Have they confused …? Well, no more onwards

There is a big difference between the two based on the structure to the functional point of view … So let’s explore some of them.

  1. Most enzymes are proteinaceous in nature, remember that most ribozymes are not all RNA molecules … while … Hormones are peptides, steroids, etc.
  2. Enzymes are a part of the biochemical reactions in metabolic pathways, remember only the part, but the main controller or regulator is hormones.
  3. Enzymatic activity is localized, that is, they work in the place where they are secreted, but in the case of hormones it does not happen … they can act much more than enzymes
  4. Enzymes are not transported through the blood, secreted by ducts (exocrine glands) and are non-diffusible entities, but hormones are administered to the cell or tissue in particular by transporting blood, therefore without ducts (endocrine gland) and nature is diffusible
  5. The enzymatic action voluntarily means that it can be modified but the hormonal action is involuntary.
  1. Enzyme-:
  • They are your biological catalysts.
  • They do not participate in a reaction but accelerate the reaction most of the time.
  • They are very particular in function.
  • A particular enzyme is activated in a particular place. They are highly specific and perform specific functions.
  • You can understand this through a key and lock model that explains that the lock is the activation site and the key is the enzyme, which is unique to each lock.
  • There are six types of enzymes:
  1. Oxide reductases: redox catalytic reactions, also called dehydrogenase a. E.g. Cytochrome
  2. Transferases: transfer of the chemical group with a substrate pair. E.g. Hexokinase
  3. Hydrolases: hydrolysis of compounds such as ether, ester, peptide, glycosidic bonds, cc bonds. E.g. Hill and esterase
  4. Lyases- Catalyze non-hydro lyric cleavage, for example. Aldolase, smoke.
  5. Isomerases- Intervonversions of isomers.
  6. Ligases: unites two molecules. eg Acetyl Coa carboxylase.

The abbreviated way to remember all these enzymes is – OTHLIL!

  1. Hormones: –
  • They are responsible for growth and maturation in their bodies.
  • They cause puberty.
  • They are secreted by special glands and their secretions are nothing more than hormones.
  • Two types of glands that secrete hormones are Endocrine and Exocrine.
  1. Endocrines: they are glands without ducts and their secretions are poured directly into the blood so that they are found throughout the body. Example: pituitary, thyroid, parathyroid, ovary, testicles, etc.
  2. Exocrine glands: these are glands with the presence of special ducts that carry secretions. Its secretions are not found everywhere around the body. Example: tear, salivary, gastric and intestinal glands.

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